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Novel Piperazinyl-Quinazoline-4-one Analogs: Design, Synthesis and Evaluation of In Vitro Biological Activity |
DUBLIN | CORE | METADATA ITEM | METADATA FOR THIS DOCUMENT |
1 | Title | Title of Document | Novel Piperazinyl-Quinazoline-4-one Analogs: Design, Synthesis and Evaluation of In Vitro Biological Activity |
2 | Creator | Author's name, affiliation, country | K. N. MYANGAR*, T. N. AKHAJA, D. R. NAIK and J. P. RAVAL Department of Pharmaceutical Chemistry, Ashok & Rita Patel Institute of Integrated Study and Research in Biotechnology and Allied Sciences (ARIBAS), ADIT Campus,
New Vallabh Vidhyanagar – 388 121, Dist: Anand, Gujarat, India |
3 | Subject | Dicipline(s) | Chemical Science |
3 | Subject | Keywords | Piperazine, 2-Chloromethyl-3-(N-isonicotinamide-yl)-4Hquinazolinone, Antitubercular activity |
4 | Description | Abstract | A series of novel 2-[4-substituted-piperazinyl-methyl]-3-[N-isonicotinamide-yl]-quinazoline-4-one (4a-l) were designed, synthesized, characterized and evaluated for in vitro antitubercular, antibacterial and antifungal activity. Compounds 4f, 4h and 4l exhibited excellent antitubercular activity against mycobacterium tuberculosis H37Rv. |
5 | Publishers | Organizing agency, location | WWW Publications, India |
6 | Contributor | Sponsor(s) | - |
7 | Date | Date (YYYY-MM-DD) | - |
8 | Type | Status & genre | Peer-reviewed Article |
8 | Type | Type | |
9 | Formate | File Formate | PDF |
10 | Identifier | Uniform Resource Identifier | Click Here |
10 | Identifier | Digital Object Identifier | |
11 | Source | Journal/conference title; vol., no. (Year) | Chemical Science Transactions, Volume 1 , Number (3), (2012) |
12 | Lanuguage | English=en | en |
13 | Relation | Supp.files | |
14 | Coverage | | - |
15 | Copyright | Copyright and permissions | |
Chemical Science Transactions | Chem Sci Trans | CST | Online Chemistry Journal | Open Access
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