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Effects of Shaddock (Citrus maxima) Fruit Juice on Glucose Tolerance and Lipid Profile in Type-II Diabetic Rats

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1TitleTitle of DocumentEffects of Shaddock (Citrus maxima) Fruit Juice on Glucose Tolerance and Lipid Profile in Type-II Diabetic Rats
2CreatorAuthor's name, affiliation, country A. OYEDEPOT and S.O. BABARINDE
Department of Biological Sciences, Adeleke University, Ede P.M.B. 250, Ede, Osun State, Nigeria
3SubjectDicipline(s) Chemical Science
3SubjectKeywords Shaddock fruit juice (SFJ), Diabetes mellitus, Blood Glucose, Cholesterol, Lipid parameters
4DescriptionAbstract Cirus maxima commonly known as Shaddock has been proved for hypoglycaemic effects. The objective of the present study was to evaluate the effects of Shaddock (C.maxima) fruit juice on glucose tolerance and lipid profile in streptozotocin (STZ) induced type-II diabetic rat. Two days old neonatal pups (7–10 g) were used and they were made diabetic by intraperitoneally (i.p.) injection of 90 mg/kg STZ in citrate buffer solution. Different groups of animals were treated by 25% and 50% Shaddock fruit juice (SFJ) for 8 weeks. After 8 weeks treatment biochemical parameters from blood serum were analyzed. The significant differences of glucose, cholesterol, HDL, LDL, triglyceride, in 50% SFJ treated group compare to diabetic group were found. Therefore we conclude from this present study that Shaddock fruit juice has beneficial effects on glucose tolerance and lipid profile in streptozotocin-induced type-II diabetic rat.
5PublishersOrganizing agency, location WWW Publications, India
6Contributor Sponsor(s) -
7DateDate (YYYY-MM-DD) -
8TypeStatus & genre Peer-reviewed Article
8TypeType
9FormateFile Formate PDF
10IdentifierUniform Resource Identifier Click Here
10IdentifierDigital Object Identifier
11SourceJournal/conference title; vol., no. (Year)Chemical Science Transactions, Volume  2 , Number  (1), (2013)
12LanuguageEnglish=en en
13RelationSupp.files
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Chemical Science Transactions | Chem Sci Trans | CST | Online Chemistry Journal | Open Access
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