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Spectrophotometric Determination of Valacyclovir in Pharmaceutical Formulations

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1TitleTitle of DocumentSpectrophotometric Determination of Valacyclovir in Pharmaceutical Formulations
2CreatorAuthor's name, affiliation, country G. SRIHARI, N. RAMI REDDY, K. NAGARAJA SETTY and I.E. CHAKRAVARTHI
Department of Chemistry, S.B.S.Y.M. Degree College, Kurnool (Dt), Andhra Pradesh, India
Department of Chemistry, Government College for Men, Kurnool (Dt), Andhra Pradesh, India
Department of Chemistry, Rayalaseema University, Kurnool (Dt), Andhra Pradesh, India
3SubjectDicipline(s) Chemical Science
3SubjectKeywords Spctrophotometry, Valacyclovir, para dimethyl amino benzaldehyde, Formulations
4DescriptionAbstract A simple spectrophotometric method has been developed for the estimation of valacyclovir in pharmaceutical preparations. The method is based on the reaction of the valacyclovir with methanolic solution of para dimethyl amino benzaldehyde (PDAB) in acidic condition producing Schiff base having absorption maximum at 400 nm. Beer’s law is obeyed in the concentration of 50-250 µg/mL of valacyclovir. Statistical analysis proves that the proposed method is reproducible and selective for the estimation of valacyclovir in bulk drug and in its tablet dosage form.
5PublishersOrganizing agency, location WWW Publications, India
6Contributor Sponsor(s) -
7DateDate (YYYY-MM-DD) -
8TypeStatus & genre Peer-reviewed Article
8TypeType
9FormateFile Formate PDF
10IdentifierUniform Resource Identifier Click Here
10IdentifierDigital Object Identifier
11SourceJournal/conference title; vol., no. (Year)Chemical Science Transactions, Volume  2 , Number  (1), (2013)
12LanuguageEnglish=en en
13RelationSupp.files
14Coverage -
15CopyrightCopyright and permissions
Chemical Science Transactions | Chem Sci Trans | CST | Online Chemistry Journal | Open Access
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