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RP-HPLC Method for Simultaneous Estimation of Atenolol, Hydrochlorothiazide and Losarton in Tablet Dosage form |
| DUBLIN | CORE | METADATA ITEM | METADATA FOR THIS DOCUMENT |
| 1 | Title | Title of Document | RP-HPLC Method for Simultaneous Estimation of Atenolol, Hydrochlorothiazide and Losarton in Tablet Dosage form |
| 2 | Creator | Author's name, affiliation, country | R. SHARMA, S. KHANNA and G. P. MISHRA
School of Pharmacy, Devi Ahilya Vishwavidyalaya, Takshshila Campus, Khandwa Road, Indore-452017, M.P., India |
| 3 | Subject | Dicipline(s) | Chemical Science |
| 3 | Subject | Keywords | RP-HPLC, Simultaneous Estimation, Validation, Atenolol, Hydrochlorothiazide, Losartan |
| 4 | Description | Abstract | The present work describes a simple, sensitive, accurate and rapid reverse phase high performance liquid chromatographic method for simultaneous estimation and validation of atenolol, hydrochlorothiazide and losartan in tablet dosage form. Chromatography was performed on a 25 cm × 4.6 mm i.d, 5 µm particle, C18 column with use of mixture of (A) acetonitrile, methanol (65:35) and (B) 10 mM sodium dihydrogen phosphate monohydrate buffer with 0.4% v/v triethylamine and mixture of A:B (60:40 v/v) adjusted to pH 3.0 with o-phosphoric acid (5% v/v) was used as a mobile phase at a flow rate of 1.5 mL/min. The chromatograms were recorded at 230 nm. The linearity range was found 1-25 µg/mL, 1-25 µg/mL and 1-25 µg/mL for atenolol, hydrochlorothiazide and losartan respectively. |
| 5 | Publishers | Organizing agency, location | WWW Publications, India |
| 6 | Contributor | Sponsor(s) | - |
| 7 | Date | Date (YYYY-MM-DD) | - |
| 8 | Type | Status & genre | Peer-reviewed Article |
| 8 | Type | Type | |
| 9 | Formate | File Formate | PDF |
| 10 | Identifier | Uniform Resource Identifier | Click Here |
| 10 | Identifier | Digital Object Identifier | |
| 11 | Source | Journal/conference title; vol., no. (Year) | Chemical Science Transactions, Volume 2 , Number (S1), (2013) |
| 12 | Lanuguage | English=en | en |
| 13 | Relation | Supp.files | |
| 14 | Coverage | | - |
| 15 | Copyright | Copyright and permissions | |
Chemical Science Transactions | Chem Sci Trans | CST | Online Chemistry Journal | Open Access
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