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Design, Synthesis and Pharmacological Evaluation of New Series of Pyrazolines Based Thiazolidin-4-one Derivatives |
DUBLIN | CORE | METADATA ITEM | METADATA FOR THIS DOCUMENT |
1 | Title | Title of Document | Design, Synthesis and Pharmacological Evaluation of New Series of Pyrazolines Based Thiazolidin-4-one Derivatives |
2 | Creator | Author's name, affiliation, country | PINKA PATEL, DEEPA GOR and P. S. PATEL K. K Shah Jarodwala Maninagar Science College, Ahmedabad-8, India
Department of Chemistry, Sheth L. H. Science College, Mansa-382845, India |
3 | Subject | Dicipline(s) | Chemical Science |
3 | Subject | Keywords | Synthesis, Pyrazoline, Chalcones, Schiff base, DMSO, Antimicrobial activity |
4 | Description | Abstract | We have prepared 2-{4-[2-{5-(4-chlorophenyl)-3-(4-methoxyphenyl)-4,5-dihydro-pyrazol-1-yl}-2-oxoethoxy]phenyl}-3-(substituted phenyl)-1,3-thiazolidin-4-one form N-[{4-[2-{5-(4-chloro-phenyl)-3-(4-methoxyphenyl)-4,5-dihydro-pyrazol-1-yl}-2-oxoethoxy]phenyl}methylene] substituted aniline and thioglycolic acid. Compound having an excellent properties regarding as per as anti cancer and HIV as compared to this compound. Physical properties of pure crystallized substance of 2-{4-[2-{5-(4-chlorophenyl)-3-(4-methoxyphenyl)-4,5-dihydro-pyrazol-1-yl}-2-oxoethoxy]phenyl}-3-(subs-tituted-phenyl)-1,3-thiazolidin-4-one substituted aniline like M.P elementary analysis and spectral data of compound and such as IR and NMR will be evaluated and confirm the structure of compound. All the synthesized products were evaluated for their antimicrobial activity. All the compounds were tested for their antibacterial and antifungal activities by broth dilution method. |
5 | Publishers | Organizing agency, location | WWW Publications, India |
6 | Contributor | Sponsor(s) | - |
7 | Date | Date (YYYY-MM-DD) | - |
8 | Type | Status & genre | Peer-reviewed Article |
8 | Type | Type | |
9 | Formate | File Formate | PDF |
10 | Identifier | Uniform Resource Identifier | Click Here |
10 | Identifier | Digital Object Identifier | |
11 | Source | Journal/conference title; vol., no. (Year) | Chemical Science Transactions, Volume 2 , Number (4), (2013) |
12 | Lanuguage | English=en | en |
13 | Relation | Supp.files | |
14 | Coverage | | - |
15 | Copyright | Copyright and permissions | |
Chemical Science Transactions | Chem Sci Trans | CST | Online Chemistry Journal | Open Access
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