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Synthesis, Characterization and Antimicrobial Activity of Some Newly Synthesized 1,3-Thiazolidin-4-one Derivatives |
| DUBLIN | CORE | METADATA ITEM | METADATA FOR THIS DOCUMENT |
| 1 | Title | Title of Document | Synthesis, Characterization and Antimicrobial Activity of Some Newly Synthesized 1,3-Thiazolidin-4-one Derivatives |
| 2 | Creator | Author's name, affiliation, country | ARJUNSINGH K.RANA, SUNIL B. LADE, MAYUR J. JOSHI and NIRAV M. SHAH
Department of Chemistry, Navjivan Science College, Dahod-389 151, Gujarat, India
Oxygen Healthcare Limited, Ahmedabad, India |
| 3 | Subject | Dicipline(s) | Chemical Science |
| 3 | Subject | Keywords | 1,3-Thiazolidin-4-one, 2-Chloro-6, 8-dimethyl quinoline-3-carboxaldehyde, Schiff base, Antimicrobial evaluation |
| 4 | Description | Abstract | A series of 10 new 1,3-thiazolidin-4-one (3a-3j) were synthesized from different schiff base of N-[(1E)-(3-chloro-5,7-dimethyl-2-naphthyl) methylene]aniline (2a-2j) with thioaceticacid. The chemical structures of these compounds were confirmed by means of 1H NMR, IR and mass analysis. Newly synthesized compounds were screened in vitro for their antimicrobial activity against varieties of bacterial strains such Staphylococcus epidermidis, Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa and fungi strain Aspergillus niger at 40 µg/mL. The resulted of compounds shows that chloro and flouro substituted 1,3-thiazolidine-4-one derivatives are showing quite well activity as compare to the other functional groups. |
| 5 | Publishers | Organizing agency, location | WWW Publications, India |
| 6 | Contributor | Sponsor(s) | - |
| 7 | Date | Date (YYYY-MM-DD) | - |
| 8 | Type | Status & genre | Peer-reviewed Article |
| 8 | Type | Type | |
| 9 | Formate | File Formate | PDF |
| 10 | Identifier | Uniform Resource Identifier | Click Here |
| 10 | Identifier | Digital Object Identifier | |
| 11 | Source | Journal/conference title; vol., no. (Year) | Chemical Science Transactions, Volume 2 , Number (1), (2013) |
| 12 | Lanuguage | English=en | en |
| 13 | Relation | Supp.files | |
| 14 | Coverage | | - |
| 15 | Copyright | Copyright and permissions | |
Chemical Science Transactions | Chem Sci Trans | CST | Online Chemistry Journal | Open Access
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