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Rapid and Efficient Synthesis of 2,3-Dihydro-1H-1,5-Benzodiazepines Catalyzed by Chloroacetic Acid Screened among Various Aliphatic Acids under Solvent Free Conditions

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1TitleTitle of DocumentRapid and Efficient Synthesis of 2,3-Dihydro-1H-1,5-Benzodiazepines Catalyzed by Chloroacetic Acid Screened among Various Aliphatic Acids under Solvent Free Conditions
2CreatorAuthor's name, affiliation, country AKSHDEEP SANDHAR and RAJESH K. SINGH
Pharmaceutical Chemistry Division, Shivalik College of Pharmacy (Under Local Govt Deptt., Punjab) Nangal, Distt.Rupnagar, Punjab-140126, India
3SubjectDicipline(s) Chemical Science
3SubjectKeywords 1, 5-Benzodiazepines, o-Phenylenediamine, Ketones, Aliphatic acids, Chloroacetic acid, Solvent free conditions
4DescriptionAbstract A series of 1, 5-benzodiazepines were synthesized by condensation of o-phenylenediamine with different ketones and effect of different aliphatic acids used as catalyst was studied. Among the various acids screened, chloroacetic acid came out to be a versatile catalyst and the corresponding products were obtained in good to excellent isolated yields (85-94%) under solvent free conditions.
5PublishersOrganizing agency, location WWW Publications, India
6Contributor Sponsor(s) -
7DateDate (YYYY-MM-DD) -
8TypeStatus & genre Peer-reviewed Article
8TypeType
9FormateFile Formate PDF
10IdentifierUniform Resource Identifier Click Here
10IdentifierDigital Object Identifier
11SourceJournal/conference title; vol., no. (Year)Chemical Science Transactions, Volume  2 , Number  (1), (2013)
12LanuguageEnglish=en en
13RelationSupp.files
14Coverage -
15CopyrightCopyright and permissions
Chemical Science Transactions | Chem Sci Trans | CST | Online Chemistry Journal | Open Access
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