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Synthesis and In Vitro Antioxidant Evaluation of Some Indole-2-carboxylic Acid-Aryl Amine Conjugates |
| DUBLIN | CORE | METADATA ITEM | METADATA FOR THIS DOCUMENT |
| 1 | Title | Title of Document | Synthesis and In Vitro Antioxidant Evaluation of Some Indole-2-carboxylic Acid-Aryl Amine Conjugates |
| 2 | Creator | Author's name, affiliation, country | NAGARAJA NAIK, V. SHARATH, H. VIJAY KUMAR and H. SWETHA
Department of Studies in Chemistry, University of Mysore, Manasagangotri,
Mysore-570006, Karnataka, India
Department of Organic Chemistry, Indian Institute of Science,
Banglore-570012, Karnataka, India
Plantation Products, Spices & Flavour Technology,
Central Food Technological and Research Institute, Mysore-570006, Karnataka, India |
| 3 | Subject | Dicipline(s) | Chemical Science |
| 3 | Subject | Keywords | Free radicals, Antioxidant activity, Indole-2-carboxylic acid, Aryl amines |
| 4 | Description | Abstract | A simple and efficient protocol for the synthesis of novel indole-2-carboxylic acid analogues having aryl amine moieties (2a-k) has been described. The synthesized compounds were characterized by spectroscopic techniques (IR, 1H NMR, 13C NMR and MS-EI) and further screened for their antioxidant activity by using various in vitro assays such as 2,2-diphenyl-1-picrylhydrazyl (DPPH•) scavenging assay, 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) (ABTS•+) radical scavenging activity, ferric reducing antioxidant power, cupric ion reducing ability method and phosphomolybdate method. In all the antioxidant assays performed, compounds 2b, 2d, 2e and 2f showed promising antioxidant activity. Whereas, compound 2c displayed potent antioxidant activity. |
| 5 | Publishers | Organizing agency, location | WWW Publications, India |
| 6 | Contributor | Sponsor(s) | - |
| 7 | Date | Date (YYYY-MM-DD) | - |
| 8 | Type | Status & genre | Peer-reviewed Article |
| 8 | Type | Type | |
| 9 | Formate | File Formate | PDF |
| 10 | Identifier | Uniform Resource Identifier | Click Here |
| 10 | Identifier | Digital Object Identifier | |
| 11 | Source | Journal/conference title; vol., no. (Year) | Chemical Science Transactions, Volume 2 , Number (1), (2013) |
| 12 | Lanuguage | English=en | en |
| 13 | Relation | Supp.files | |
| 14 | Coverage | | - |
| 15 | Copyright | Copyright and permissions | |
Chemical Science Transactions | Chem Sci Trans | CST | Online Chemistry Journal | Open Access
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