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Synthesis, Characterization, Antibacterial, Antifungal and Anticancer Studies of a New Antimetabolite:
N-[(Diphenylamino)methyl]acetamide and Some of Its Inner Transition Metal Chelates

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1TitleTitle of DocumentSynthesis, Characterization, Antibacterial, Antifungal and Anticancer Studies of a New Antimetabolite:
N-[(Diphenylamino)methyl]acetamide and Some of Its Inner Transition Metal Chelates
2CreatorAuthor's name, affiliation, country L. MURUGANANDAM, K. KRISHNA KUMAR and K. BALASUBRAMANIAN
Department of Chemistry, Saranathan College of Engineering, Tiruchirapalli-12, India
Department of Chemistry, National Institute of Technology, Tiruchirapalli-15, India
3SubjectDicipline(s) Chemical Science
3SubjectKeywords Physicochemical, Tuberculosis, Monosubstituted, Antimetabolite, Lipophilic
4DescriptionAbstract N-[(Diphenylamino)methyl]acetamide was synthesized using Mannich reaction and its complexes of cerium(IV), thorium(IV) and dioxouranium(VI) were prepared and characterized by elemental analysis and various spectral studies. The bidendate chelation of ligand, bonding through carbonyl oxygen and azomethine nitrogen is suggested. Based on spectral and magnetic studies, hexa coordinate geometry is assigned for all the complexes. The complexes were screened for their antibacterial, antifungal and anticancer activities. They show positive results.
5PublishersOrganizing agency, location WWW Publications, India
6Contributor Sponsor(s) -
7DateDate (YYYY-MM-DD) -
8TypeStatus & genre Peer-reviewed Article
8TypeType
9FormateFile Formate PDF
10IdentifierUniform Resource Identifier Click Here
10IdentifierDigital Object Identifier DOI:10.7598/cst2013.335
11SourceJournal/conference title; vol., no. (Year)Chemical Science Transactions, Volume  2 , Number  (2), (2013)
12LanuguageEnglish=en en
13RelationSupp.files
14Coverage -
15CopyrightCopyright and permissions
Chemical Science Transactions | Chem Sci Trans | CST | Online Chemistry Journal | Open Access
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