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Analytical Method Development for Determination of Performance of Adapalene in Adapalene 0.1% Gel Formulation Using Manual Diffusion Cell |
DUBLIN | CORE | METADATA ITEM | METADATA FOR THIS DOCUMENT |
1 | Title | Title of Document | Analytical Method Development for Determination of Performance of Adapalene in Adapalene 0.1% Gel Formulation Using Manual Diffusion Cell |
2 | Creator | Author's name, affiliation, country | S.S.DEO, F. INAM and N. P. KARMARKAR Department of Chemistry, Institute of Science,
Rabindranath Tagore Road, Civil Lines, Nagpur-440010, India |
3 | Subject | Dicipline(s) | Chemical Science |
3 | Subject | Keywords | In vitro release, Manual diffusion cell, Synthetic support membranes, Receptor medium, Reverse phase-high performance liquid chromatography |
4 | Description | Abstract | A simple, reliable and reproducible method applicable for topical creams is developed to monitor the in vitro performance of adapalene 0.1% cream formulations using manual diffusion cell with suitable synthetic membrane and receptor medium. The membranes which have permeability similar to skin and receptor media that can maintain the sink conditions have been selected. For solid oral dosage forms such as tablets, extensive study and analytical methods were developed to evaluate the in vitro performance of the drug. But for semisolid dosage forms, no official guideline exists to measure its performance. Therefore, to quantify the performance of the adapalene 0.1% cream, in vitro release method is developed with manual diffusion cell and analysed using high performance liquid chromatography. |
5 | Publishers | Organizing agency, location | WWW Publications, India |
6 | Contributor | Sponsor(s) | - |
7 | Date | Date (YYYY-MM-DD) | - |
8 | Type | Status & genre | Peer-reviewed Article |
8 | Type | Type | |
9 | Formate | File Formate | PDF |
10 | Identifier | Uniform Resource Identifier | Click Here |
10 | Identifier | Digital Object Identifier | |
11 | Source | Journal/conference title; vol., no. (Year) | Chemical Science Transactions, Volume 2 , Number (1), (2013) |
12 | Lanuguage | English=en | en |
13 | Relation | Supp.files | |
14 | Coverage | | - |
15 | Copyright | Copyright and permissions | |
Chemical Science Transactions | Chem Sci Trans | CST | Online Chemistry Journal | Open Access
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