Chemical Science Transactions | Chem Sci Trans | CST | Online Chemistry Journal | Open Access
Home | Table of Contents | Submit an article | Subscribe | Login | Register

Indexing Metadata

Analytical Method Development for Determination of Performance of Adapalene in Adapalene 0.1% Gel Formulation Using Manual Diffusion Cell

DUBLINCOREMETADATA ITEM METADATA FOR THIS DOCUMENT
1TitleTitle of DocumentAnalytical Method Development for Determination of Performance of Adapalene in Adapalene 0.1% Gel Formulation Using Manual Diffusion Cell
2CreatorAuthor's name, affiliation, country S.S.DEO, F. INAM and N. P. KARMARKAR
Department of Chemistry, Institute of Science, Rabindranath Tagore Road, Civil Lines, Nagpur-440010, India
3SubjectDicipline(s) Chemical Science
3SubjectKeywords In vitro release, Manual diffusion cell, Synthetic support membranes, Receptor medium, Reverse phase-high performance liquid chromatography
4DescriptionAbstract A simple, reliable and reproducible method applicable for topical creams is developed to monitor the in vitro performance of adapalene 0.1% cream formulations using manual diffusion cell with suitable synthetic membrane and receptor medium. The membranes which have permeability similar to skin and receptor media that can maintain the sink conditions have been selected. For solid oral dosage forms such as tablets, extensive study and analytical methods were developed to evaluate the in vitro performance of the drug. But for semisolid dosage forms, no official guideline exists to measure its performance. Therefore, to quantify the performance of the adapalene 0.1% cream, in vitro release method is developed with manual diffusion cell and analysed using high performance liquid chromatography.
5PublishersOrganizing agency, location WWW Publications, India
6Contributor Sponsor(s) -
7DateDate (YYYY-MM-DD) -
8TypeStatus & genre Peer-reviewed Article
8TypeType
9FormateFile Formate PDF
10IdentifierUniform Resource Identifier Click Here
10IdentifierDigital Object Identifier
11SourceJournal/conference title; vol., no. (Year)Chemical Science Transactions, Volume  2 , Number  (1), (2013)
12LanuguageEnglish=en en
13RelationSupp.files
14Coverage -
15CopyrightCopyright and permissions
Chemical Science Transactions | Chem Sci Trans | CST | Online Chemistry Journal | Open Access
Home | Table of Contents | Submit an article | Subscribe | Login | Register