| DUBLIN | CORE | METADATA ITEM | METADATA FOR THIS DOCUMENT |
| 1 | Title | Title of Document | Facile and Green Syntheses of Unsymmetrically Substituted 3-(1-Benzyl-1H-indol-3-yl)-2-(1-ethyl-1H-indole-3-carbonyl)-acrylonitrile and Study of their Antimicrobial Activities |
| 2 | Creator | Author's name, affiliation, country | G. THIRUPATHI, M. VENKATANARAYANA,
P. K. DUBEY and Y. BHARATHI KUMARI
Department of Chemistry, Jawaharlal Nehru Technological University,
Hyderabad College of Engineering, Kukatpally, Hyderabad (A.P)-500085, India |
| 3 | Subject | Dicipline(s) | Chemical Science |
| 3 | Subject | Keywords | Indole-3-carboxyaldehyde, 3-Cyanoacetylindole, Knoevenagel reaction, L-tryptophan, Physical grinding |
| 4 | Description | Abstract | Facile and green syntheses of unsymmetrically substituted-3-(1-benzyl-1H-indol-3-yl)-2-(1-ethyl-1H-indole-3-carbonyl)-acrylonitriles 5(a-d) is being reported. L-tryptophan has been utilized as an efficient and eco-friendly catalyst in the solvent free condition under the grind stone method at room temperature for Knoevenagel condensation of N-benzyl indole-3-carboxyaldehyde (2) with the active methylene compounds, 3-cyanoacetylindole 3(a-d) at room temperature to afford substituted-3-(1-benzyl-1H-indol-3-yl)-2-(1H-indole-3-carbonyl)-acrylonitrile 4(a-d) respectively. Subsequently these products were treated with DES and K2CO3 in the solvent free condition under the grind stone method at room temperature to afford the corresponding substituted-3-(1-benzyl-1H-indol-3-yl)-2- (1-ethyl-1H-indole-3-carbonyl)-acrylonitrile 5(a-d). The antibacterial and antifungal activities of 4(a-d) and 5(a-d) have been studied. |
| 5 | Publishers | Organizing agency, location | WWW Publications, India |
| 6 | Contributor | Sponsor(s) | - |
| 7 | Date | Date (YYYY-MM-DD) | - |
| 8 | Type | Status & genre | Peer-reviewed Article |
| 8 | Type | Type | |
| 9 | Formate | File Formate | PDF |
| 10 | Identifier | Uniform Resource Identifier | Click Here |
| 10 | Identifier | Digital Object Identifier | |
| 11 | Source | Journal/conference title; vol., no. (Year) | Chemical Science Transactions, Volume 2 , Number (1), (2013) |
| 12 | Lanuguage | English=en | en |
| 13 | Relation | Supp.files | |
| 14 | Coverage | | - |
| 15 | Copyright | Copyright and permissions | |
