Indexing Metadata
New RP-UFLC Method for Estimation of Xanthinol Nicotinate in Pharmaceutical Dosage Form |
| DUBLIN | CORE | METADATA ITEM | METADATA FOR THIS DOCUMENT |
| 1 | Title | Title of Document | New RP-UFLC Method for Estimation of Xanthinol Nicotinate in Pharmaceutical Dosage Form |
| 2 | Creator | Author's name, affiliation, country | SAGAR SUMAN PANDA, B.V.V. RAVI KUMAR,
PINKAL KUMAR PATEL and
JNYANARANJAN PANDA
Department of Pharmaceutical Analysis and Quality Assurance,
Roland Institute of Pharmaceutical Sciences, Berhampur, Odisha, India |
| 3 | Subject | Dicipline(s) | Chemical Science |
| 3 | Subject | Keywords | Xanthinol, RP-UFLC, Validation, Stability, Nicotinic acid |
| 4 | Description | Abstract | A novel, accurate and precise RP-UFLC method for determination of xanthinol nicotinate has been developed and validated. Separation was achieved on an Enable C18G column (250 mm × 4.6 mm i.d., 5 µm) using acetonitrile: 10 mM TBAHS (40:60, v/v) as mobile phase at a flow rate of 0.8 mL/min and PDA detection at 274 nm. Linearity was observed in the concentration range of 1.0-60 µg/mL (r2=0.999). The method was validated for accuracy, precision, stability, specificity, robustness and system suitability. Forced degradation was performed by using HCl, NaOH, H2O2, thermal and UV radiation. The method was used successfully for the determination of xanthinol nicotinate in tablet dosage form. |
| 5 | Publishers | Organizing agency, location | WWW Publications, India |
| 6 | Contributor | Sponsor(s) | - |
| 7 | Date | Date (YYYY-MM-DD) | - |
| 8 | Type | Status & genre | Peer-reviewed Article |
| 8 | Type | Type | |
| 9 | Formate | File Formate | PDF |
| 10 | Identifier | Uniform Resource Identifier | Click Here |
| 10 | Identifier | Digital Object Identifier | |
| 11 | Source | Journal/conference title; vol., no. (Year) | Chemical Science Transactions, Volume 2 , Number (2), (2013) |
| 12 | Lanuguage | English=en | en |
| 13 | Relation | Supp.files | |
| 14 | Coverage | | - |
| 15 | Copyright | Copyright and permissions | |
Chemical Science Transactions | Chem Sci Trans | CST | Online Chemistry Journal | Open Access
|
