Indexing Metadata
Synthesis, Structural Study and Biological
Activity of Bridgehead Nitrogen Containing
Triazolo-thiadiazine Derivatives |
DUBLIN | CORE | METADATA ITEM | METADATA FOR THIS DOCUMENT |
1 | Title | Title of Document | Synthesis, Structural Study and Biological
Activity of Bridgehead Nitrogen Containing
Triazolo-thiadiazine Derivatives |
2 | Creator | Author's name, affiliation, country | PRADIP P. DEOHATE P. G. Department of Chemistry,
Shri Radhakisan Laxminarayan Toshniwal College of Science, Akola-444001, India |
3 | Subject | Dicipline(s) | Chemical Science |
3 | Subject | Keywords | Synthesis, Biological activity, Triazolo-thiadiazines |
4 | Description | Abstract | A facile synthesis of 6,7-di-[substituted]-phenyl-3-pyridin-4-yl-5H-[1,2,4]-triazolo-[3,4-b]-[1,3,4]-thiadiazines have been carried out by reacting 4-amino-3-mercapto-5-pyridin-4-yl-4H-[1,2,4]-triazole with substituted benzoins in presence of potassium hydroxide. The required 4-amino-3-mercapto-5-pyridin-4-yl-4H-[1,2,4]-triazole was synthesized by reacting isoniazide with carbon-disulphide and potassium hydroxide followed by the addition of hydrazine hydrate. The acetylation of triazolo-thiadiazines afforded monoacetyl derivatives. The constitution of synthesized compounds have been delineated on the basis of chemical transformation, elemental analysis, equivalent weight determination and IR, 1H NMR spectral studies. The title compounds have been assayed for their biological activity against gram-positive as well as gram-negative microorgansms. |
5 | Publishers | Organizing agency, location | WWW Publications, India |
6 | Contributor | Sponsor(s) | - |
7 | Date | Date (YYYY-MM-DD) | - |
8 | Type | Status & genre | Peer-reviewed Article |
8 | Type | Type | |
9 | Formate | File Formate | PDF |
10 | Identifier | Uniform Resource Identifier | Click Here |
10 | Identifier | Digital Object Identifier | |
11 | Source | Journal/conference title; vol., no. (Year) | Chemical Science Transactions, Volume 2 , Number (2), (2013) |
12 | Lanuguage | English=en | en |
13 | Relation | Supp.files | |
14 | Coverage | | - |
15 | Copyright | Copyright and permissions | |
Chemical Science Transactions | Chem Sci Trans | CST | Online Chemistry Journal | Open Access
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