Indexing Metadata
Synthesis, Structural Study and Antimicrobial
Screening of Substituted Bis-benzothiazole Derivatives |
| DUBLIN | CORE | METADATA ITEM | METADATA FOR THIS DOCUMENT |
| 1 | Title | Title of Document | Synthesis, Structural Study and Antimicrobial
Screening of Substituted Bis-benzothiazole Derivatives |
| 2 | Creator | Author's name, affiliation, country | PRADIP P. DEOHATE
P. G. Department of Chemistry, Shri Radhakisan Laxminarayan Toshniwal College of Science, Akola-444001, India |
| 3 | Subject | Dicipline(s) | Chemical Science |
| 3 | Subject | Keywords | Synthesis, Structural study, Antimicrobial screening, Bis-benzothiazoles |
| 4 | Description | Abstract | A series of {4-[4-(6-substituted-benzothiazol-2-yl-amino)-3-carboxy-benzyl]-2-carboxy-phenyl}-6-substituted-benzothiazol-2-yl-amines have been synthesized by oxidative cyclization of 1-{4-[4-(3-aryl thiocarbamido)-3-carboxy-benzyl]-2-carboxy-phenyl}-3-aryl thiocarbamides using the solution of bromine in chloroform followed by the basification with dilute ammonium hydroxide solution. Initially 1-{4-[4-(3-aryl thiocarbamido)-3-carboxy-benzyl]-2-carboxy-phenyl}-3-aryl thio-carbamides were prepared by the interaction of different aryl isothiocyanates with 4,4’-methylene-bis-(anthranilic acid). The latter was obtained by treating the mixture of anthranilic acid and concentrated hydrochloric acid with 3% aqueous formaldehyde followed by neutralization with sodium hydroxide. The acetylation of bis-benzothiazoles afforded di-acetyl derivatives. The structures of synthesized compounds have been established on the basis of chemical transformation, elemental analysis, equivalent weight determination and IR, 1H NMR spectral studies. The title compounds have been assayed for their biological activity against gram-positive as well as gram-negative microorganisms. |
| 5 | Publishers | Organizing agency, location | WWW Publications, India |
| 6 | Contributor | Sponsor(s) | - |
| 7 | Date | Date (YYYY-MM-DD) | - |
| 8 | Type | Status & genre | Peer-reviewed Article |
| 8 | Type | Type | |
| 9 | Formate | File Formate | PDF |
| 10 | Identifier | Uniform Resource Identifier | Click Here |
| 10 | Identifier | Digital Object Identifier | |
| 11 | Source | Journal/conference title; vol., no. (Year) | Chemical Science Transactions, Volume 2 , Number (2), (2013) |
| 12 | Lanuguage | English=en | en |
| 13 | Relation | Supp.files | |
| 14 | Coverage | | - |
| 15 | Copyright | Copyright and permissions | |
Chemical Science Transactions | Chem Sci Trans | CST | Online Chemistry Journal | Open Access
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