| DUBLIN | CORE | METADATA ITEM | METADATA FOR THIS DOCUMENT |
| 1 | Title | Title of Document | Designing and Biological Evaluation of New Benzimidazole Compounds |
| 2 | Creator | Author's name, affiliation, country | CH. SRIDEVI*, M. MARI KANNAN, G. ABHINAYANI and N. SRAVYA
Department of Pharmaceutical Chemistry, Geethanjali College of Pharmacy, Cheeryal(V), Keesara(M), Hyderabad.501301, A.P, India |
| 3 | Subject | Dicipline(s) | Chemical Science |
| 3 | Subject | Keywords | Benzimidazole, o-Phenylene diamine, Aromatic aldehydes, Chalcones, Antibacterial activity |
| 4 | Description | Abstract | Benzimidazole derivatives play important role in medical field with many important properties. The potency of these clinically useful drugs in the treatment of bacterial infections and other activities encouraged the development of some more potent and significant compounds. This research article is summarized to know about the chemistry of different derivatives of substituted benzimidazoles along with their pharmacological activities. In the present research the new benzimidazole derivatives were synthesized. The reaction was carried out by condensing o-phenylene diamine with carboxylic acid by using Phillip’s condensation. The free N-H group in benzimidazole was allowed for acetylation. The acetylated product was made to react with different aromatic aldehydes in the presence of alkali to give different chalcones (III A-III F) by aldol condensation. The compounds were synthesized in good yield and their structures were confirmed by M.P, TLC and spectral data. All the synthesized compounds were screened for their antibacterial activity. |
| 5 | Publishers | Organizing agency, location | WWW Publications, India |
| 6 | Contributor | Sponsor(s) | - |
| 7 | Date | Date (YYYY-MM-DD) | - |
| 8 | Type | Status & genre | Peer-reviewed Article |
| 8 | Type | Type | |
| 9 | Formate | File Formate | PDF |
| 10 | Identifier | Uniform Resource Identifier | Click Here |
| 10 | Identifier | Digital Object Identifier | |
| 11 | Source | Journal/conference title; vol., no. (Year) | Chemical Science Transactions, Volume 2 , Number (3), (2013) |
| 12 | Lanuguage | English=en | en |
| 13 | Relation | Supp.files | |
| 14 | Coverage | | - |
| 15 | Copyright | Copyright and permissions | |
