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Spectrophotometric Methods for the Assay of Ceftazidime in Bulk and its Pharmaceutical Formulations

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1TitleTitle of DocumentSpectrophotometric Methods for the Assay of Ceftazidime in Bulk and its Pharmaceutical Formulations
2CreatorAuthor's name, affiliation, country L. MOHAN KRISHNA, P. JAYACHANDRA REDDY, V. JAYA SANKAR REDDY and
K.V. S. PRASADA RAO
Krishna Teja Pharmacy College, Tirupati, India
Rahul Institute of Pharmaceutical Sciences, Chirla, India
3SubjectDicipline(s) Chemical Science
3SubjectKeywords Spectrophotometry, NBS, Ceftazidime , Gallocyanine
4DescriptionAbstract Three visible spectrophotometric methods have been described for the assay of ceftazidime (CTZ) either in bulk form or dosage forms. Methods A-C are based on the oxidation of CTZ with an excess of oxidant (N-bromosuccinimide (NBS) in methods A and B or chloramine-T (CAT) in method C) in acidic medium. The unreacted oxidant was then estimated colorimetrically by using an oxidisable dye (Celistine blue (CB) in method A or gallocyanine (GC) in method C) or by p-N-methyl aminophenol sulphate (PMAP)- sulphanilamide (SA) reagent in method B. Regression analysis of Beer’s law plots showed good concentration range 2.0-10.0 µg/mL, 4.0-16.0 µg/mL and 1.0-8.0 µg/mL for methods A, B and C respectively and gives reproducible results.
5PublishersOrganizing agency, location WWW Publications, India
6Contributor Sponsor(s) -
7DateDate (YYYY-MM-DD) -
8TypeStatus & genre Peer-reviewed Article
8TypeType
9FormateFile Formate PDF
10IdentifierUniform Resource Identifier Click Here
10IdentifierDigital Object Identifier
11SourceJournal/conference title; vol., no. (Year)Chemical Science Transactions, Volume  2 , Number  (2), (2013)
12LanuguageEnglish=en en
13RelationSupp.files
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