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Design and Biological Evaluation of 2,2'-Dinitrodiphenylmethane Derivatives

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1TitleTitle of DocumentDesign and Biological Evaluation of 2,2'-Dinitrodiphenylmethane Derivatives
2CreatorAuthor's name, affiliation, country A. JEPA MALAR*, M. CHRISTUDHAS and G. ALLEN GNANA RAJ
Department of Chemistry, N. M. Christian College, Marthandam, Tamilnadu-629165, India
Department of Chemistry, Scott Christian College (Autonomous), Nagercoil, Tamilnadu-629003, India
3SubjectDicipline(s) Chemical Science
3SubjectKeywords Sandmeyer’s reaction, Cuprous bromide, Hydrobromic acid, Hypophosphorous acid, Antimicrobial activity
4DescriptionAbstract Synthesis of 4,4',5,5'-tetrabromo-2,2'-dinitrodiphenylmethane and 5,5'-dibromo-2,2'-dinitrodiphenylmethane from 4,4'-diamino-5,5'-dibromo-2,2'-dinitrodiphenylmethane are reported. 4,4',5,5'-Tetrabromo-2,2'-dinitrodiphenylmethane (TBNDPM) have been synthesized by a simple and convenient method employing Sandmeyer’s reaction of 4,4'-diamino-5,5'-dibromo-2,2'-dinitrodiphenylmethane (ABNDPM) with cuprous bromide and hydrobromic acid and 5,5'-dibromo-2,2'-dinitrodiphenylmethane (BNDPM) has obtained by treatment of ABNDPM with hypophosphorous acid and cuprous oxide. The structures of the synthesized compounds are assigned on the basis of elemental and spectral analysis (UV-visible, FTIR and 1H-NMR). The synthesized compounds have been evaluated for the antibacterial and antifungal efficacy.
5PublishersOrganizing agency, location WWW Publications, India
6Contributor Sponsor(s) -
7DateDate (YYYY-MM-DD) -
8TypeStatus & genre Peer-reviewed Article
8TypeType
9FormateFile Formate PDF
10IdentifierUniform Resource Identifier Click Here
10IdentifierDigital Object Identifier
11SourceJournal/conference title; vol., no. (Year)Chemical Science Transactions, Volume  2 , Number  (3), (2013)
12LanuguageEnglish=en en
13RelationSupp.files
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15CopyrightCopyright and permissions
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