DUBLIN | CORE | METADATA ITEM | METADATA FOR THIS DOCUMENT |
1 | Title | Title of Document | Indirect Spectrophotometric Determination of
Cephalexin in Pharmaceutical Formulations |
2 | Creator | Author's name, affiliation, country | REBWAR O. HASSAN Department of Chemistry, College of Science, University of Salahaddin, Erbil, Iraq |
3 | Subject | Dicipline(s) | Chemical Science |
3 | Subject | Keywords | Indirect spectrophotometric, Cephalexin, Pharmaceutical products |
4 | Description | Abstract | Simple, reliable and sensitive indirect spectrophotometric method was developed for the determination of cephalexin in pharmaceutical products without pretreatment. The method was based on the fading effect of the cephalexin on developed color product resulted from the bromination reaction of NBS with p-anisidine in acidic medium, subsequently vanished colored species was measured at 522 nm. Cephalexin acts in accordance with the Beer’s law, under optimum conditions, at concentration ranges 1.5-10.0 μg/mL (R = 0.9949) with detection limit of 0.90 μg/mL. The relative standard deviation and error percent for 3 replicate determinations were found to be 2.2% and 1.75%, respectively. The proposed method was applied to the determination of cephalexin in different pharmaceutical products. A comparison of the method reported is made with standard official method and can be used as a convenient analysis method for routine quality control. |
5 | Publishers | Organizing agency, location | WWW Publications, India |
6 | Contributor | Sponsor(s) | - |
7 | Date | Date (YYYY-MM-DD) | - |
8 | Type | Status & genre | Peer-reviewed Article |
8 | Type | Type | |
9 | Formate | File Formate | PDF |
10 | Identifier | Uniform Resource Identifier | Click Here |
10 | Identifier | Digital Object Identifier | |
11 | Source | Journal/conference title; vol., no. (Year) | Chemical Science Transactions, Volume 2 , Number (4), (2013) |
12 | Lanuguage | English=en | en |
13 | Relation | Supp.files | |
14 | Coverage | | - |
15 | Copyright | Copyright and permissions | |