Chemical Science Transactions | Chem Sci Trans | CST | Online Chemistry Journal | Open Access
Home | Table of Contents | Submit an article | Subscribe | Login | Register

Indexing Metadata

Indirect Spectrophotometric Determination of Cephalexin in Pharmaceutical Formulations

DUBLINCOREMETADATA ITEM METADATA FOR THIS DOCUMENT
1TitleTitle of DocumentIndirect Spectrophotometric Determination of Cephalexin in Pharmaceutical Formulations
2CreatorAuthor's name, affiliation, country REBWAR O. HASSAN
Department of Chemistry, College of Science, University of Salahaddin, Erbil, Iraq
3SubjectDicipline(s) Chemical Science
3SubjectKeywords Indirect spectrophotometric, Cephalexin, Pharmaceutical products
4DescriptionAbstract Simple, reliable and sensitive indirect spectrophotometric method was developed for the determination of cephalexin in pharmaceutical products without pretreatment. The method was based on the fading effect of the cephalexin on developed color product resulted from the bromination reaction of NBS with
p-anisidine in acidic medium, subsequently vanished colored species was measured at 522 nm. Cephalexin acts in accordance with the Beer’s law, under optimum conditions, at concentration ranges 1.5-10.0 μg/mL
(R = 0.9949) with detection limit of 0.90 μg/mL. The relative standard deviation and error percent for 3 replicate determinations were found to be 2.2% and 1.75%, respectively. The proposed method was applied to the determination of cephalexin in different pharmaceutical products. A comparison of the method reported is made with standard official method and can be used as a convenient analysis method for routine quality control.
5PublishersOrganizing agency, location WWW Publications, India
6Contributor Sponsor(s) -
7DateDate (YYYY-MM-DD) -
8TypeStatus & genre Peer-reviewed Article
8TypeType
9FormateFile Formate PDF
10IdentifierUniform Resource Identifier Click Here
10IdentifierDigital Object Identifier DOI:10.7598/cst2013.449
11SourceJournal/conference title; vol., no. (Year)Chemical Science Transactions, Volume  2 , Number  (4), (2013)
12LanuguageEnglish=en en
13RelationSupp.files
14Coverage -
15CopyrightCopyright and permissions
Chemical Science Transactions | Chem Sci Trans | CST | Online Chemistry Journal | Open Access
Home | Table of Contents | Submit an article | Subscribe | Login | Register