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Synthesis and Antimicrobial Screening of Some Novel 2-(2-Chloroquinolin-3-yl)-3-(1-phenylamine)-1,3- thiazolidin-4-ones

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1TitleTitle of DocumentSynthesis and Antimicrobial Screening of Some Novel 2-(2-Chloroquinolin-3-yl)-3-(1-phenylamine)-1,3- thiazolidin-4-ones
2CreatorAuthor's name, affiliation, country R. A. SHASTRI
P. G. Department of Chemistry, Milind College of Science, Aurangabad 431002, India
3SubjectDicipline(s) Chemical Science
3SubjectKeywords 2-Chloro-3-formylquionline, Thioglycolic acid, 1,3-Thiazolidin-4-one
4DescriptionAbstract 2-Chloro-3-formylquinoline derivative (1) on treatment with phenyl hydrazine (2) yields Schiff’s bases 2-(2-chloroquinolin-3-yl)methylene-2-phenyl hydrazine (3a-e). Compound 3a-e on treatment with thioglycollic acid and catalytic quantity of ZnCl2 in methanol yields the title compounds 4a-e. The newly synthesized compounds 4a-e have been screened for their antibacterial and antifungal activities and their chemical structures have been elucidated by IR, NMR spectral data. Some of them exhibited significant antifungal activity.
5PublishersOrganizing agency, location WWW Publications, India
6Contributor Sponsor(s) -
7DateDate (YYYY-MM-DD) -
8TypeStatus & genre Peer-reviewed Article
8TypeType
9FormateFile Formate PDF
10IdentifierUniform Resource Identifier Click Here
10IdentifierDigital Object Identifier DOI:10.7598/cst2013.457
11SourceJournal/conference title; vol., no. (Year)Chemical Science Transactions, Volume  2 , Number  (3), (2013)
12LanuguageEnglish=en en
13RelationSupp.files
14Coverage -
15CopyrightCopyright and permissions
Chemical Science Transactions | Chem Sci Trans | CST | Online Chemistry Journal | Open Access
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