Indexing Metadata
Assay of Dexmedetomidine in Bulk Samples and Pharmaceutical Formulations by Extractive Spectrophotometry |
| DUBLIN | CORE | METADATA ITEM | METADATA FOR THIS DOCUMENT |
| 1 | Title | Title of Document | Assay of Dexmedetomidine in Bulk Samples and Pharmaceutical Formulations by Extractive Spectrophotometry |
| 2 | Creator | Author's name, affiliation, country | K.HARINADHA BABA1*, C. RAMBABU2, K. VARA PRASADA RAO3, RIYAZ AHMED KHAN4 and K. V. S. PRASADA RAO1
1Rahul Institute of Phramceutical Sciences,
Papaipalem Road, Chirala, Prakasam (D.T), A.P. Pin- 513 157, India
2Department of Chemistry, Acharya Nagarjuna University P.G. Centre, Nuzivid, India
3Vignan Institute of Pharmaceutical Technology, Visakhapatnam-46, India
4David Memorial College of Pharmacy, Yacharam, R.R.(D.T), India |
| 3 | Subject | Dicipline(s) | Chemical Science |
| 3 | Subject | Keywords | Dexmedetomidine, Ion-associates, Solubility, Spectrophotometry |
| 4 | Description | Abstract | Three simple and sensitive spectrophotometric methods (A-C) for the assay of dexmedetomidine in pure and dosage forms based on the formation of chloroform soluble ion-associates under specified experimental conditions are described. Three acidic dyes, namely Wool Fast Blue BL (WFB BL, method A), Tropaeolin ooo (Tpooo, method B), Naphthol Blue 12BR (NB 12BR, method C) were utilized. The extracts of the ion-associates exhibit absorption maxima at 580 nm, 480 nm, and 590 nm for methods A, B and C respectively. Beer’s law and the precision and accuracy of the methods are checked by the UV reference method. The results are reproducible with an accuracy of ±1.0%. The methods are found to be suitable for the determination of dexmedetomidine in the presence of the other ingredients that are usually present in dosage forms. |
| 5 | Publishers | Organizing agency, location | WWW Publications, India |
| 6 | Contributor | Sponsor(s) | - |
| 7 | Date | Date (YYYY-MM-DD) | - |
| 8 | Type | Status & genre | Peer-reviewed Article |
| 8 | Type | Type | |
| 9 | Formate | File Formate | PDF |
| 10 | Identifier | Uniform Resource Identifier | Click Here |
| 10 | Identifier | Digital Object Identifier | |
| 11 | Source | Journal/conference title; vol., no. (Year) | Chemical Science Transactions, Volume 4 , Number (1), (2015) |
| 12 | Lanuguage | English=en | en |
| 13 | Relation | Supp.files | |
| 14 | Coverage | | - |
| 15 | Copyright | Copyright and permissions | |
Chemical Science Transactions | Chem Sci Trans | CST | Online Chemistry Journal | Open Access
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