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Synthesis, Characterization and Antimicrobial Study of Substituted Benzopyranone Derivatives

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1TitleTitle of DocumentSynthesis, Characterization and Antimicrobial Study of Substituted Benzopyranone Derivatives
2CreatorAuthor's name, affiliation, country MOHSEN A M GOMAA
Science College, Chemistry Division, King Faisal University, Al-Hufuf-31982, Saudi Arabia Chemistry Department, Faculty of Science, Minia University, 61519 El-Minia, Egypt
3SubjectDicipline(s) Chemical Science
3SubjectKeywords Chromones, Benzopyrane, Pyrazole, Pyrimidinthione, Biological activity
4DescriptionAbstract Reaction of 6-formylbenzopyranone derivative (1) with 2-(1-phenyl-ethylylidene) malononitrile led to formation of 7-hydroxy-chromen-6-yl-(1-phenyl-allylidene) malononitrile (2). Reaction of 2 with hydrazines led to formation of the corresponding aminopyrazole derivatives 3 and 4. While reaction of 2 with thiourea led to formation of 4,6-diaminopyrimidin-2-thione derivative 5. Hydrolysis of 2 with ammonium hydroxide afforded 2-cyano-5-(7-hydroxy-5-methoxy-2-methyl-4-oxo-4H-chromene-6-yl)-3-phenyl-penta-2,4-dienoic acidamide (6). The structures of the new compounds were confirmed on the basis of the elemental analysis and spectral data. All the synthesized products were evaluated for their antimicrobial activity.
5PublishersOrganizing agency, location WWW Publications, India
6Contributor Sponsor(s) -
7DateDate (YYYY-MM-DD) -
8TypeStatus & genre Peer-reviewed Article
8TypeType
9FormateFile Formate PDF
10IdentifierUniform Resource Identifier Click Here
10IdentifierDigital Object Identifier
11SourceJournal/conference title; vol., no. (Year)Chemical Science Transactions, Volume  2 , Number  (3), (2013)
12LanuguageEnglish=en en
13RelationSupp.files
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15CopyrightCopyright and permissions
Chemical Science Transactions | Chem Sci Trans | CST | Online Chemistry Journal | Open Access
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