Chemical Science Transactions | Chem Sci Trans | CST | Online Chemistry Journal | Open Access
Home | Table of Contents | Submit an article | Subscribe | Login | Register

Indexing Metadata

Synthesis and Antimicrobial Activity of Some Isoxazole Derivatives of Thiophene

DUBLINCOREMETADATA ITEM METADATA FOR THIS DOCUMENT
1TitleTitle of DocumentSynthesis and Antimicrobial Activity of Some Isoxazole Derivatives of Thiophene
2CreatorAuthor's name, affiliation, country KAMALA CHAND GAUTAM*and DHARMCHAND PRASAD SINGH
College of Pharmacy, IFTM, Moradabad (U.P.), India
College of Pharmacy, SR group of Institutions, Jhansi (U.P.), India
3SubjectDicipline(s) Chemical Science
3SubjectKeywords 2-Acetyl thiophene, Chalcones, Hydroxylamine hydrochloride, Isoxazoles, Antimicrobial activity
4DescriptionAbstract A series of new chalcones were synthesized by the reaction of 2-acetyl thiophene and substituted bezaldehydes. Then the chalcones were made to undergo cyclization reaction with hydroxylamine hydrochloride in ethanol to afford the synthesis of isoxazole derivatives of thiophene. The synthesized compounds were purified and their structures were elucidated with the help of IR and 1H NMR spectroscopy. The compounds were screened for antimicrobial activity by disc diffusion method. The result suggested that the four compounds were moderately to highly active.
5PublishersOrganizing agency, location WWW Publications, India
6Contributor Sponsor(s) -
7DateDate (YYYY-MM-DD) -
8TypeStatus & genre Peer-reviewed Article
8TypeType
9FormateFile Formate PDF
10IdentifierUniform Resource Identifier Click Here
10IdentifierDigital Object Identifier DOI:10.7598/cst2013.478
11SourceJournal/conference title; vol., no. (Year)Chemical Science Transactions, Volume  2 , Number  (3), (2013)
12LanuguageEnglish=en en
13RelationSupp.files
14Coverage -
15CopyrightCopyright and permissions
Chemical Science Transactions | Chem Sci Trans | CST | Online Chemistry Journal | Open Access
Home | Table of Contents | Submit an article | Subscribe | Login | Register