| DUBLIN | CORE | METADATA ITEM | METADATA FOR THIS DOCUMENT |
| 1 | Title | Title of Document | Determination of Emtricitabine by Derivative Spectrophotometric Method in Pharmaceutical Dosage Forms |
| 2 | Creator | Author's name, affiliation, country | A. NARENDRA*, D. DEEPIKA and M. MATHRUSRI ANNAPURNA
Micro Advanced Research Centre, Bangalore, Karnataka, India
Vijaya Institue of Pharmaceutical Sciences for Women, Vijayawada, A.P, India
GITAM Institute of Pharmacy, GITAM University, Visakhapatnam, A.P., India |
| 3 | Subject | Dicipline(s) | Chemical Science |
| 3 | Subject | Keywords | Emtricitabine, Derivative spectroscopy, Area under curve |
| 4 | Description | Abstract | Three simple, precise and accurate spectrophotometric methods have been developed for the estimation of emtricitabine in bulk and pharmaceutical formulations. Emtricitabine exhibits maximum absorbance at
282.0 nm in method A. The amplitude shows at 269.0-298.0 nm in method B and method C is based on calculation of area under curve (AUC) in the wavelength region of 272.0-292.0 nm. The drug obeys the Beer-Lambert’s law in the concentration range of 1.0-100 μg/mL in all three methods. The methods were validated by following the analytical performance parameters suggested by the International Conference on Harmonization. All validation parameters were within the acceptable range. The developed methods were successfully applied to estimate the amount of emtricitabine in bulk and pharmaceutical dosage forms. |
| 5 | Publishers | Organizing agency, location | WWW Publications, India |
| 6 | Contributor | Sponsor(s) | - |
| 7 | Date | Date (YYYY-MM-DD) | - |
| 8 | Type | Status & genre | Peer-reviewed Article |
| 8 | Type | Type | |
| 9 | Formate | File Formate | PDF |
| 10 | Identifier | Uniform Resource Identifier | Click Here |
| 10 | Identifier | Digital Object Identifier | |
| 11 | Source | Journal/conference title; vol., no. (Year) | Chemical Science Transactions, Volume 2 , Number (3), (2013) |
| 12 | Lanuguage | English=en | en |
| 13 | Relation | Supp.files | |
| 14 | Coverage | | - |
| 15 | Copyright | Copyright and permissions | |
