Indexing Metadata
New Spectrophotometric Methods for the Quantitative Analysis of Fluorometholone in Ophthalmic Suspensions |
| DUBLIN | CORE | METADATA ITEM | METADATA FOR THIS DOCUMENT |
| 1 | Title | Title of Document | New Spectrophotometric Methods for the Quantitative Analysis of Fluorometholone in Ophthalmic Suspensions |
| 2 | Creator | Author's name, affiliation, country | A.NARENDRA, D.DEEPIKA and M.MATHRUSRI ANNAPURNA
Micro Advanced Research Centre, Bangalore, Karnataka, India
VijayaInstitue of Pharmaceutical Sciences for women, Vijayawada, A.P, India
GITAM Institute of Pharmacy, GITAM University, Visakhapatnam, A.P., India |
| 3 | Subject | Dicipline(s) | Chemical Science |
| 3 | Subject | Keywords | Fluorometholone, Eye drops, Validation |
| 4 | Description | Abstract | Two simple, rapid and sensitive spectrophotometric methods were developed for the determination of Fluorometholone in pharmaceutical formulations in methanol (Method A) and Octane sulfonic acid buffer (pH 3.0) (Method B). Beer’s law was obeyed over the concentration range 0.1-80 µg/mL in both methods. The linear regression equations were found to be y = 0.040x + 0.005 and y = 0.040x - 0.013 in Method A and B respectively. The % RSD was found to be 0.76 and 0.97 in Method A as well as 0.58 and 0.49 in Method B for intra-day and inter-day precision studies. The % RSD in accuracy studies was also found to be less than 2.0. The proposed methods are simple and suitable for the determination of Fluorometholone in pharmaceutical formulations. No interferences were observed from the excipients in the formulations. The methods were validated according to ICH guidelines. |
| 5 | Publishers | Organizing agency, location | WWW Publications, India |
| 6 | Contributor | Sponsor(s) | - |
| 7 | Date | Date (YYYY-MM-DD) | - |
| 8 | Type | Status & genre | Peer-reviewed Article |
| 8 | Type | Type | |
| 9 | Formate | File Formate | PDF |
| 10 | Identifier | Uniform Resource Identifier | Click Here |
| 10 | Identifier | Digital Object Identifier | |
| 11 | Source | Journal/conference title; vol., no. (Year) | Chemical Science Transactions, Volume 3 , Number (1), (2014) |
| 12 | Lanuguage | English=en | en |
| 13 | Relation | Supp.files | |
| 14 | Coverage | | - |
| 15 | Copyright | Copyright and permissions | |
Chemical Science Transactions | Chem Sci Trans | CST | Online Chemistry Journal | Open Access
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