Indexing Metadata
Synthesis and Antibacterial Activity of Some
1-Phenyl-3-aryl-5-(4-(3-propanoloxy) phenyl)-1H-pyrazoles |
| DUBLIN | CORE | METADATA ITEM | METADATA FOR THIS DOCUMENT |
| 1 | Title | Title of Document | Synthesis and Antibacterial Activity of Some
1-Phenyl-3-aryl-5-(4-(3-propanoloxy) phenyl)-1H-pyrazoles |
| 2 | Creator | Author's name, affiliation, country | ANJU GOYAL, NEELAM JAIN and SANDEEP JAIN
Chitkara College of Pharmacy, Rajpura, Patiala-140 401 (Punjab), India
Department of Pharmaceutical Education and Research, Bhagat Phool Singh Mahila Vishwavidyalaya,
Khanpur Kalan, Sonipat-131305 (Haryana), India
Drug Discovery and Research Laboratory, Department of Pharmaceutical Sciences, Guru Jambheshwar University of Science and Technology, Hisar-125001 (Haryana), India |
| 3 | Subject | Dicipline(s) | Chemical Science |
| 3 | Subject | Keywords | Chalcones, 1H-pyrazoles, Antibacterial activity, Minimum inhibitory concentration |
| 4 | Description | Abstract | A series of 1-phenyl-3-aryl-5-(4-(3-propanoloxy) phenyl)-1H-pyrazoles were synthesized from chalcones and studied for their in vitro antibacterial activity. Chalcones i.e.,1-aryl-3-(4-hydroxyphenyl) prop-2-en-1-ones (1) on reaction with phenyl hydrazine in presence of acetic acid and few drops of HCl yielded the corresponding 1-phenyl-3-aryl-5-(4-hydroxyphenyl)-1H-pyrazoles (2) which on further reaction with 3-chloropropanol furnished the title compounds (3). These compounds were characterized by CHN analyses, IR, mass and 1H NMR spectral data. All the compounds were evaluated for their in vitro antibacterial activity against two gram negative strains (Escherichia coli and Pseudomonas aeruginosa) and two gram positive strains (Bacillus subtilis and Staphylococcus aureus) and their minimum inhibitory concentration (MIC) were determined. |
| 5 | Publishers | Organizing agency, location | WWW Publications, India |
| 6 | Contributor | Sponsor(s) | - |
| 7 | Date | Date (YYYY-MM-DD) | - |
| 8 | Type | Status & genre | Peer-reviewed Article |
| 8 | Type | Type | |
| 9 | Formate | File Formate | PDF |
| 10 | Identifier | Uniform Resource Identifier | Click Here |
| 10 | Identifier | Digital Object Identifier | |
| 11 | Source | Journal/conference title; vol., no. (Year) | Chemical Science Transactions, Volume 3 , Number (1), (2014) |
| 12 | Lanuguage | English=en | en |
| 13 | Relation | Supp.files | |
| 14 | Coverage | | - |
| 15 | Copyright | Copyright and permissions | |
Chemical Science Transactions | Chem Sci Trans | CST | Online Chemistry Journal | Open Access
|
