Indexing Metadata
Identification, Isolation and Characterization of Unknown Impurity in Daunorubicin Hydrochloride |
| DUBLIN | CORE | METADATA ITEM | METADATA FOR THIS DOCUMENT |
| 1 | Title | Title of Document | Identification, Isolation and Characterization of Unknown Impurity in Daunorubicin Hydrochloride |
| 2 | Creator | Author's name, affiliation, country | AJAY SINGH RAWAT*, VITTHAL BUCHUDE, KAMLESH CHAUHAN, DIVYESH PATEL, RITESH PATEL, CHANDRAKANT BELWAL and ANAND VARDHAN
Sterling Biotech Limited, Jambusar State Highway, Village Masar 391421, Taluka, Padra, Distt: Vadodara Gujarat India |
| 3 | Subject | Dicipline(s) | Chemical Science |
| 3 | Subject | Keywords | Daunorubicin, Unknown impurity, Chromatography, Preparative HPLC, Lyophilization, NMR, LC-MS, LC/MS/MS |
| 4 | Description | Abstract | An unknown impurity in the bulk drug daunorubicin hydrochloride observed at 1.79 RRT was detected by the means of reverse phase isocratic High performance liquid chromatography (HPLC). This impurity was isolated, enriched and was subjected to mass and NMR spectral studies. Based on the spectral data the impurity was identified as (8S,10S)-8-ethyl-10-[(2S,4S,5S,6S)-4-amino-5-hydroxy-6-methyl-oxan-2-yl]oxy-6,8,11-trihydroxy-1-methoxy-9,10-dihydro-7H-tetracene-5,12-dione also known as 13-deoxy-daunorubicin. |
| 5 | Publishers | Organizing agency, location | WWW Publications, India |
| 6 | Contributor | Sponsor(s) | - |
| 7 | Date | Date (YYYY-MM-DD) | - |
| 8 | Type | Status & genre | Peer-reviewed Article |
| 8 | Type | Type | |
| 9 | Formate | File Formate | PDF |
| 10 | Identifier | Uniform Resource Identifier | Click Here |
| 10 | Identifier | Digital Object Identifier | |
| 11 | Source | Journal/conference title; vol., no. (Year) | Chemical Science Transactions, Volume 3 , Number (3), (2014) |
| 12 | Lanuguage | English=en | en |
| 13 | Relation | Supp.files | |
| 14 | Coverage | | - |
| 15 | Copyright | Copyright and permissions | |
Chemical Science Transactions | Chem Sci Trans | CST | Online Chemistry Journal | Open Access
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