Indexing Metadata
Development and Validation of HPLC Method for the Quantification of Anticancer Peptide |
| DUBLIN | CORE | METADATA ITEM | METADATA FOR THIS DOCUMENT |
| 1 | Title | Title of Document | Development and Validation of HPLC Method for the Quantification of Anticancer Peptide |
| 2 | Creator | Author's name, affiliation, country | JAGATHEESH KALIYAPERUMAL, PAVANKUMAR PADARTHI
KOWSALYA RANGASAMY and ELANGOVAN NAMASIVAYAM*
Molecular Pharmacology Research Laboratory, Department of Biotechnology,
Periyar University, Salem, Tamilnadu-636011, India |
| 3 | Subject | Dicipline(s) | Chemical Science |
| 3 | Subject | Keywords | Cancer, RP-HPLC, Quantitative analysis, Peptide, Analytical method |
| 4 | Description | Abstract | As the prevalence of cancer persists, the development of new and more advanced therapies remains a main concern in the health research. In this work the development and validation of HPLC method for the quantification of anticancer peptide were checked for analytical validation parameters were accuracy, precision (repeatability and reproducibility), specificity, sensitivity (limit of detection and limit of quantification) and linearity. The accuracy and precision of the method have been tested and the coefficients of variation have been found to be less than 2% according to ICH validation guideline. The linearity range was found to be 5-35 μg/mL, LOD-5.65 μg/mL and LOQ-17.1322 μg/mL respectively. In conclusion, a new RP-HPLC method has been developed and validated successfully for the quantitative analysis for the peptide in this study. |
| 5 | Publishers | Organizing agency, location | WWW Publications, India |
| 6 | Contributor | Sponsor(s) | - |
| 7 | Date | Date (YYYY-MM-DD) | - |
| 8 | Type | Status & genre | Peer-reviewed Article |
| 8 | Type | Type | |
| 9 | Formate | File Formate | PDF |
| 10 | Identifier | Uniform Resource Identifier | Click Here |
| 10 | Identifier | Digital Object Identifier | |
| 11 | Source | Journal/conference title; vol., no. (Year) | Chemical Science Transactions, Volume 3 , Number (3), (2014) |
| 12 | Lanuguage | English=en | en |
| 13 | Relation | Supp.files | |
| 14 | Coverage | | - |
| 15 | Copyright | Copyright and permissions | |
Chemical Science Transactions | Chem Sci Trans | CST | Online Chemistry Journal | Open Access
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