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Synthesis and Antimicrobial Evaluation of Novel Azetidinones |
DUBLIN | CORE | METADATA ITEM | METADATA FOR THIS DOCUMENT |
1 | Title | Title of Document | Synthesis and Antimicrobial Evaluation of Novel Azetidinones |
2 | Creator | Author's name, affiliation, country | SANJAY D. PRAJAPATI and M. K. THAKUR* Department of Chemistry, Municipal Arts and Urban Science College,
Mehsana-384002 (Guj.), India |
3 | Subject | Dicipline(s) | Chemical Science |
3 | Subject | Keywords | 3-(4-Aminophenylsulfonyl)-1,3,4-oxadiazole-2(3H)-thione, Schiff base, Azetidinone, Antibacterial activity. |
4 | Description | Abstract | 3-(4-Aminophenylsulfonyl)-1,3,4-oxadiazole-2(3H<)-thione (1) undergoes facile condensation with different aromatic aldehydes to afford the corresponding 3-(4-(substituted benzylideneamino)phenylsulfonyl)-1,3,4-oxadiazole-2(3H)-thione (2a-e) in good yields. Cyclocondensation of compounds (2a-e) with chloroacetyl chloride yields 3-chloro-4- subsituted phenyl-1-(4-(2-thioxo-1,3,4-oxadiazol-3(2H)-ylsulfonyl)phenyl)azetidin-2-one (3a-e). The structures of these compounds were established on the basis of analytical and spectral data. All the newly synthesized compounds were evaluated for their antibacterial and antifungal activities |
5 | Publishers | Organizing agency, location | WWW Publications, India |
6 | Contributor | Sponsor(s) | - |
7 | Date | Date (YYYY-MM-DD) | - |
8 | Type | Status & genre | Peer-reviewed Article |
8 | Type | Type | |
9 | Formate | File Formate | PDF |
10 | Identifier | Uniform Resource Identifier | Click Here |
10 | Identifier | Digital Object Identifier | |
11 | Source | Journal/conference title; vol., no. (Year) | Chemical Science Transactions, Volume 3 , Number (3), (2014) |
12 | Lanuguage | English=en | en |
13 | Relation | Supp.files | |
14 | Coverage | | - |
15 | Copyright | Copyright and permissions | |
Chemical Science Transactions | Chem Sci Trans | CST | Online Chemistry Journal | Open Access
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