| DUBLIN | CORE | METADATA ITEM | METADATA FOR THIS DOCUMENT |
| 1 | Title | Title of Document | Development and Validation of a Stability-Indicating
Liquid Chromatographic Method for the Determination of Cefditoren Pivoxil in Presence of Degradation Products |
| 2 | Creator | Author's name, affiliation, country | M. MATHRUSRI ANNAPURNA and B. VENKATESH
Department of Pharmaceutical Analysis & Quality Assurance,
GITAM Institute of Pharmacy, GITAM University, Visakhapatnam, India |
| 3 | Subject | Dicipline(s) | Chemical Science |
| 3 | Subject | Keywords | Cefditoren pivoxil, Stability-indicating, Liquid chromatography, Validation, ICH |
| 4 | Description | Abstract | A novel stability indicating liquid chromatographic method was developed for the determination of Cefditoren pivoxil in presence of degradation products using Zorbax SB C18 (150 mm × 4.6 mm i.d., 3.5 μm particle size) column with a flow rate 1.0 mL/min (UV detection 210 nm). Linearity was observed over a concentration range 0.1–200 μg/mL with regression equation y = 34809 x + 30603 (R2 = 0.9994). Forced degradation studies were performed and Cefditoren pivoxil is reported to be highly sensitive towards alkaline conditions in comparison to oxidation. The method was validated as per ICH guidelines. |
| 5 | Publishers | Organizing agency, location | WWW Publications, India |
| 6 | Contributor | Sponsor(s) | - |
| 7 | Date | Date (YYYY-MM-DD) | - |
| 8 | Type | Status & genre | Peer-reviewed Article |
| 8 | Type | Type | |
| 9 | Formate | File Formate | PDF |
| 10 | Identifier | Uniform Resource Identifier | Click Here |
| 10 | Identifier | Digital Object Identifier | |
| 11 | Source | Journal/conference title; vol., no. (Year) | Chemical Science Transactions, Volume 3 , Number (2), (2014) |
| 12 | Lanuguage | English=en | en |
| 13 | Relation | Supp.files | |
| 14 | Coverage | | - |
| 15 | Copyright | Copyright and permissions | |
