DUBLIN | CORE | METADATA ITEM | METADATA FOR THIS DOCUMENT |
1 | Title | Title of Document | Analytical Techniques for the Determination of Erlotinib HCl in Pharmaceutical Dosage Forms by Spectrophotometry |
2 | Creator | Author's name, affiliation, country | M. MATHRUSRI ANNAPURNA, B. VENKATESH and R. KRISHNA CHAITANYA Department of Pharmaceutical Analysis & Quality Assurance,
GITAM Institute of Pharmacy, GITAM University, Visakhapatnam, India |
3 | Subject | Dicipline(s) | Chemical Science |
3 | Subject | Keywords | Erlotinib HCl, Spectrophotometry, Validation |
4 | Description | Abstract | Three simple, rapid and sensitive spectrophotometric methods were developed for the determination of Erlotinib hydrochloride in pharmaceutical formulations. Beer’s law was obeyed over a concentration range 0.5-30 µg/mL in HCl and acetate buffer and 1-30 µg/mL in phosphate buffer. The linear regression equations were found to be y = 0.0717x + 0.0083, y = 0.0676x + 0.0102 and y = 0.0638x + 0.0096 in HCl, acetate buffer and phosphate buffer respectively and the three methods were validated as per ICH guidelines. |
5 | Publishers | Organizing agency, location | WWW Publications, India |
6 | Contributor | Sponsor(s) | - |
7 | Date | Date (YYYY-MM-DD) | - |
8 | Type | Status & genre | Peer-reviewed Article |
8 | Type | Type | |
9 | Formate | File Formate | PDF |
10 | Identifier | Uniform Resource Identifier | Click Here |
10 | Identifier | Digital Object Identifier | |
11 | Source | Journal/conference title; vol., no. (Year) | Chemical Science Transactions, Volume 3 , Number (2), (2014) |
12 | Lanuguage | English=en | en |
13 | Relation | Supp.files | |
14 | Coverage | | - |
15 | Copyright | Copyright and permissions | |