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Development and Validated of Stability-Indicating RP-HPLC Method for the Analysis of Zolpidem Tartrate in Tablets

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1TitleTitle of DocumentDevelopment and Validated of Stability-Indicating RP-HPLC Method for the Analysis of Zolpidem Tartrate in Tablets
2CreatorAuthor's name, affiliation, country M. MATHRUSRI ANNAPURNA, S. BHARGAVI, S. PAVANI and B. VENKATESH
Department of Pharmaceutical Analysis & Quality Assurance, GITAM Institute of Pharmacy, GITAM University, Visakhapatnam, India
3SubjectDicipline(s) Chemical Science
3SubjectKeywords Zolpidem tartrate, RP-HPLC, Stability-indicating, ICH
4DescriptionAbstract A validated stability-indicating high-performance liquid chromatographic technique was developed for the determination of Zolpidem tartrate in pharmaceutical dosage forms. Chromatographic separation was performed on Shimadzu Model CBM-20A/20 Alite, using water: methanol: acetic acid(25: 75: 0.1, v/v) as mobile phase with a flow rate of 1.2 mL/min. Zolpidem tartrate was subjected to stress conditions (acidic, alkaline, oxidation, thermaland photolytic) and the method was validated as per ICH guidelines.
5PublishersOrganizing agency, location WWW Publications, India
6Contributor Sponsor(s) -
7DateDate (YYYY-MM-DD) -
8TypeStatus & genre Peer-reviewed Article
8TypeType
9FormateFile Formate PDF
10IdentifierUniform Resource Identifier Click Here
10IdentifierDigital Object Identifier DOI:10.7598/cst2014.832
11SourceJournal/conference title; vol., no. (Year)Chemical Science Transactions, Volume  3 , Number  (2), (2014)
12LanuguageEnglish=en en
13RelationSupp.files
14Coverage -
15CopyrightCopyright and permissions
Chemical Science Transactions | Chem Sci Trans | CST | Online Chemistry Journal | Open Access
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