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Synthesis, Characterisation and Biological Activity of a New Mannich Base and It's Metal Complexes

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1TitleTitle of DocumentSynthesis, Characterisation and Biological Activity of a New Mannich Base and It's Metal Complexes
2CreatorAuthor's name, affiliation, country M. SIVAKAMI, B. NATARAJAN* and M. VIJAYACHANDRASEKAR
Department of Chemistry, Faculty of Engineering and Technology, SRM University, Kattankulathur, Tamilnadu, India
3SubjectDicipline(s) Chemical Science
3SubjectKeywords Mannich base, SMBTU, Metal complexes, Antimicrobial activity
4DescriptionAbstract Mannich bases play a major role in biological processes. In view of this a new Mannich base 1-(2,5-dioxo pyrolidin-1-yl)(4-methoxy phenyl)(methyl)thiourea (SMBTU) was synthesized using succinimide, methoxybenzaldehyde and thiourea. The complexation behaviour of this ligand with Mn(II), Ni(II), Cu(II) and Zn(II) ions were studied. The structural features of the complexes were analyzed by elemental analysis, IR, UV-Visible, 1H, 13C NMR spectra and magnetic susceptibility measurements. The anti microbial activity of the ligand and its complexes has been extensively studied against some of the gram-positive and gram-negative bacterium. The ligand and all the metal complexes showed antimicrobial activity.
5PublishersOrganizing agency, location WWW Publications, India
6Contributor Sponsor(s) -
7DateDate (YYYY-MM-DD) -
8TypeStatus & genre Peer-reviewed Article
8TypeType
9FormateFile Formate PDF
10IdentifierUniform Resource Identifier Click Here
10IdentifierDigital Object Identifier
11SourceJournal/conference title; vol., no. (Year)Chemical Science Transactions, Volume  3 , Number  (3), (2014)
12LanuguageEnglish=en en
13RelationSupp.files
14Coverage -
15CopyrightCopyright and permissions
Chemical Science Transactions | Chem Sci Trans | CST | Online Chemistry Journal | Open Access
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