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Synthesis and Antimicrobial Evaluation of Some Substituted-3-Aryl -2,3,4,5,6,7-hexahydro-1H-inden-1-one

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1TitleTitle of DocumentSynthesis and Antimicrobial Evaluation of Some Substituted-3-Aryl -2,3,4,5,6,7-hexahydro-1H-inden-1-one
2CreatorAuthor's name, affiliation, country MANJUNATH MOGER, DARSHAN RAJ C GOVINDRAJU, RAMA MOHAN HINDUPUR and HARI NARAYAN PATI*
Advinus Therapeutics Ltd., 21 & 22, Phase II, Peenya Industrial Area, Bangalore-560058, Karnataka, India
Department of Bio-Medicinal Research, Vidya Herbs Pvt. Ltd., Bangalore-562106, Karnataka, India
3SubjectDicipline(s) Chemical Science
3SubjectKeywords Cyclopentenone, Nazarov reaction, Acetic acid, Anti-microbial activity
4DescriptionAbstract Synthesis of new cyclopentenone derivatives by reacting 1-acetyl-1-cyclohexene with various aromatic and heteroaromatic aldehydes is reported. All the new cyclopentenone derivatives were characterized by 1H, 13C NMR, IR and mass spectral data, and were further screened for their antimicrobial activity. Most of the compounds showed comparable activities with standard drug ciprofloxacin and in particular, compounds 3d, 3f, 3g and 3j showed excellent activity against all the four bacterial strains.
5PublishersOrganizing agency, location WWW Publications, India
6Contributor Sponsor(s) -
7DateDate (YYYY-MM-DD) -
8TypeStatus & genre Peer-reviewed Article
8TypeType
9FormateFile Formate PDF
10IdentifierUniform Resource Identifier Click Here
10IdentifierDigital Object Identifier
11SourceJournal/conference title; vol., no. (Year)Chemical Science Transactions, Volume  3 , Number  (4), (2014)
12LanuguageEnglish=en en
13RelationSupp.files
14Coverage -
15CopyrightCopyright and permissions
Chemical Science Transactions | Chem Sci Trans | CST | Online Chemistry Journal | Open Access
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