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Curcumin Loaded Nano Cubosomal Hydrogel: Preparation, In Vitro Characterization and Antibacterial Activity

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1TitleTitle of DocumentCurcumin Loaded Nano Cubosomal Hydrogel: Preparation, In Vitro Characterization and Antibacterial Activity
2CreatorAuthor's name, affiliation, country A. ARACHANA, K. VIJAYA SRI*, M. MADHURI and CH. AJAY KUMAR
Malla Reddy College of Pharmacy, Maisammaguda, Secunderabad-500 014, Andhra Pradesh, India
3SubjectDicipline(s) Chemical Science
3SubjectKeywords Curcumin, Glycerol mono oleate, Cubosome, Hydrogel, Characterization, Antibacterial activity
4DescriptionAbstract The objective of present investigation was to develop curcumin loaded cubosomes and evaluated for topical delivery. Curcumin-loaded cubosomes were prepared by homogenization method and prepared curcumin nano cubosomes were evaluated regarding microscopic studies, particle size analysis, zeta potential, entrapment efficiency (EE%). Cubosomes hydrogels were prepared by using carbopol as gelling agent and evaluated for appearance, pH, viscosity, entrapment efficiency, in vitro drug diffuse studies, skin irritation studies and anti bacterial activity. The particle size of the formulation was about 75.2 nm and zeta potential -24 mv. The developed curcumin loaded cubosomal hydrogel gave rise to stable, nano-sized vesicles, able to improve curcumin anti bacterial activity in topical drug delivery.
5PublishersOrganizing agency, location WWW Publications, India
6Contributor Sponsor(s) -
7DateDate (YYYY-MM-DD) -
8TypeStatus & genre Peer-reviewed Article
8TypeType
9FormateFile Formate PDF
10IdentifierUniform Resource Identifier Click Here
10IdentifierDigital Object Identifier DOI:10.7598/cst2015.913
11SourceJournal/conference title; vol., no. (Year)Chemical Science Transactions, Volume  4 , Number  (1), (2015)
12LanuguageEnglish=en en
13RelationSupp.files
14Coverage -
15CopyrightCopyright and permissions
Chemical Science Transactions | Chem Sci Trans | CST | Online Chemistry Journal | Open Access
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