Research Article
In vitro Evaluation of Some Different Brands of Alprazolam Tablets
A. ASHNAGAR, M. KOUCHAK, M. SOLTANI and A. SALIMI
ABSTRACT
Alprazolam belongs to a group of medicines called benzodiazepines. These medicines are thought to work by their action on brain chemicals. Alprazolam has sedative effects and is used to treat: (i) Anxiety and (ii) Panic attacks. The results obtained in this research by various HPLC analyses and other physicochemical tests have shown that alprazolam tablets manufactured by Dr. Abidi and Poursina Pharmaceutical Companies of Iran have the standard limits acceptable by the internationally well known Pharmacopoeia such as USP and can satisfy the needs of patients quite well and are quite comparable with Xanax® of USA and Apo-Alpraz® of Canada
Received 9 May 2007; Accepted 30 June 2007