Research Article
Synthesis and Antimicrobial Activity of
Some New Chalcones of
2-Acetyl Pyridine
Y. RAJENDRA PRASAD*, P. PRAVEEN KUMAR, P. RAVI KUMAR
and A. SRINIVASA RAO
ABSTRACT
Six new chalcones were synthesised by condensing 2-acetyl pyridine with aldehyde derivatives in dilute ethanolic potassium hydroxide solution at room temperature according to Claisen-Schmidt condensation. All these compounds were characterised by means of their IR, 1H NMR spectroscopic data and microanalyses. The antimicrobial activity of these compounds was evaluated by the cup plate method.
Received 17 July 2007; Accepted 20 September 2007