Research Article
Microwave Induced Synthesis and Anti bacterial Activity of Some 6-(2-Hyroxy phenyl)-4-(substituted phenyl) -3-oxo-2, 3, 4, 5- tetrahydro-1H-indazoles
N. S. RAO, B. BAJIA* Y. K. SRIVASTAVA and RAVINDRA KUMAR
ABSTRACT
The title compounds were Synthesized by condensation of 2-hydroxy chalcones with ethylacetoacetate to get intermediate 3,5-diaryl-6-Carbethoxy-2-cyclohexenone which were subsequently treated with hydrazine hydrate to afford the title compounds. All the transformation was carried out under microwave induced conditions. The synthesized compounds were screened for their antibacterial activity in vitro.
Received 23 March 2007; Accepted 10 May 2007