Research Article
Synthesis and Antimicrobial Activity of Some Chalcone Derivatives
Y. RAJENDRA PRASAD*, A. LAKSHMANA RAO and R. RAMBABU
ABSTRACT
In an effort to develop antimicrobial agents, a series of chalcones were prepared by Claisen-Schmidt condensation of appropriate acetophenones with appropriate aromatic aldehydes in the presence of aqueous solution of potassium hydroxide and ethanol at room temperature. The synthesized compounds were characterized by means of their IR, 1H-NMR spectral data and elemental analysis. All the compounds were tested for their antibacterial and antifungal activities by the cup plate method
Received 28 October 2007; Accepted 20 December 2007